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bindcraft

Official

End-to-end binder design with AF2 validation.

Design & Creative#modal#protein design#design campaigns#AF2 validation#BindCraft#binder design
Authoradaptyvbio
Version1.0.0
Installs0

System Documentation

What problem does it solve?

End-to-end binder design is automated with BindCraft and AF2 validation to accelerate production campaigns and improve design quality.

Core Features & Use Cases

  • End-to-end binder design and evaluation using BindCraft with integrated AF2 validation.
  • Supports multiple design protocols (fast, default, slow) and joint backbone/sequence optimization.
  • Outputs QC metrics and design campaigns suitable for experimental validation.

Quick Start

Example usage: modal run modal_bindcraft.py --target-pdb target.pdb --target-chain A --binder-lengths 70-100 --hotspots A45,A67,A89 --num-designs 50

Dependency Matrix

Required Modules

None required

Components

scriptsreferences

💻 Claude Code Installation

Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.

Please help me install this Skill:
Name: bindcraft
Download link: https://github.com/adaptyvbio/protein-design-skills/archive/main.zip#bindcraft

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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