boltzgen

Official

All-atom protein design with BoltzGen diffusion.

Authoradaptyvbio
Version1.0.0
Installs0

System Documentation

What problem does it solve?

BoltzGen enables all-atom protein design using diffusion models, empowering simultaneous backbone and side-chain optimization for precise binding predictions.

Core Features & Use Cases

  • All-atom design with diffusion for accurate backbone and side-chain packing.
  • YAML-based configuration for reproducible campaigns, including binding to proteins, peptides, or small molecules.
  • End-to-end workflows: design, inverse folding, structure prediction, and ranking, executable via Modal or local installations.

Quick Start

Run a basic BoltzGen design with a YAML binder config: modal run modal_boltzgen.py --input-yaml binder.yaml --protocol protein-anything --num-designs 50

Dependency Matrix

Required Modules

None required

Components

scriptsreferences

💻 Claude Code Installation

Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.

Please help me install this Skill:
Name: boltzgen
Download link: https://github.com/adaptyvbio/protein-design-skills/archive/main.zip#boltzgen

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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