spatial-register

Official

Align spatial transcriptomics slices

AuthorTianGzlab
Version1.0.0
Installs0

System Documentation

What problem does it solve?

This Skill automates the alignment of spatial coordinates across multiple tissue slices, which is crucial for integrating and analyzing serial sections or replicate experiments in spatial transcriptomics.

Core Features & Use Cases

  • Multi-slice Alignment: Aligns N slices to a reference slice using methods like Procrustes or PASTE.
  • Coordinate Transformation: Updates spatial coordinates to reflect the aligned positions.
  • Use Case: Aligning serial sections of a tumor to reconstruct a 3D spatial map or comparing gene expression patterns across replicate tissue samples.

Quick Start

Align my spatial transcriptomics slices using the PASTE method.

Dependency Matrix

Required Modules

scanpyscipynumpypandasmatplotlib

Components

scriptsreferences

💻 Claude Code Installation

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Please help me install this Skill:
Name: spatial-register
Download link: https://github.com/TianGzlab/OmicsClaw/archive/main.zip#spatial-register

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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