What problem does it solve? Researchers analyzing gene or protein lists need to know which biological pathways are statistically enriched, but interacting with the Reactome Analysis and Content Service APIs directly requires handling dozens of endpoints, tokens, and output formats manually. ## Core Features & Use Cases - Pathway Enrichment Analysis: Submit gene or protein lists for overrepresentation analysis with FDR and p-value filtering, then retrieve results later via tokens. - Identifier Mapping & Cross-Referencing: Map identifiers (UniProt, Ensembl, gene symbols, ChEBI) to Reactome entities and across external databases. - Pathway Navigation & Visualization: Traverse pathway hierarchies, inspect reaction participants, and export diagrams as PNG or SVG with gene highlighting. - Use Case: Given a list of differentially expressed genes like TP53, BRCA1, and EGFR, run an enrichment analysis, filter to significant pathways at FDR 0.05, and export a highlighted diagram of Cell Cycle, Mitotic (R-HSA-69278). ## Quick Start Ask the assistant to run a Reactome pathway enrichment analysis on your gene list and show the top significant pathways.
