gene-list-curator

Curate literature-backed gene lists into a structured table with references.

64|12|Updated Apr 7, 2026
One-click install
npx skills add https://github.com/MDhewei/bioinfor-claw --skill gene-list-curator
Or copy as Structured Prompt for Agent▼
Please help me install this Agent Skill.
Skill: gene-list-curator
Source: https://github.com/MDhewei/bioinfor-claw/tree/main/gene-list-analysis/curate-gene-list-by-function
Command: npx skills add https://github.com/MDhewei/bioinfor-claw --skill gene-list-curator

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires openpyxl, and includes scripts (resource) and references (resource) components.

What problem does it solve?

Curate literature-backed gene or protein lists for a requested function, pathway, molecular class, or regulator type, then normalize them into a structured table or workbook.

Core Features & Use Cases

  • Build populated candidate lists by querying authoritative databases (UniProt for high-confidence entries and NCBI Gene for aliases).
  • Merge and normalize data into a unified schema with fields like Gene name, Protein ID, Organism, Functional class, Evidence or role, PMID, References, and Notes.
  • Use cases include transcription factors, pathway gene sets, receptor families, chromatin regulators, and methylation readers.

Quick Start

Generate a curated, publication-ready gene list for transcription factors in Homo sapiens with identifiers and references, exported as a CSV.

Frequently Asked Questions about gene-list-curator

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I curate a literature-backed gene list for a specific pathway or functional class?▼

To curate a literature-backed gene list, this Skill queries UniProt and NCBI Gene to identify candidates for a requested function, then normalizes them into a structured table with Gene name, Protein ID, Organism, and PMID references.

What is the output format for normalized gene sets curated from UniProt and NCBI Gene?▼

The normalized gene sets are output as a structured table or workbook containing fixed schema fields: Gene name, Protein ID, Organism, Functional class, Evidence or role, PMID, References, and Notes, with an optional UniProt accession.

Can I build a publication-ready transcription factor list for Homo sapiens with references?▼

Yes, you can generate a curated, publication-ready transcription factor list for Homo sapiens that includes gene names, protein identifiers, and literature references, exported as a structured CSV file.

Does this gene list curation tool support chromatin regulators and receptor families across organisms?▼

Yes, this gene list curation tool applies to function-specific gene sets including chromatin regulators, receptor families, transcription factors, and methylation readers across organisms, merging data into a unified schema.

Do I need openpyxl installed to export curated gene lists as a workbook?▼

Yes, openpyxl is a required dependency to export the curated and normalized gene lists as a structured workbook, as the Skill relies on this library for workbook generation and formatting.

What's the best way to normalize gene aliases from NCBI Gene into a structured dataset?▼

The best way to normalize gene aliases is to query NCBI Gene for alias data, merge them with high-confidence UniProt entries, and map them into a structured dataset with functional class, evidence, and reference fields.