protein-qc
OfficialQuality-control filters for protein designs.
Authoradaptyvbio
Version1.0.0
Installs0
System Documentation
What problem does it solve?
This Skill automates quality-control checks for protein design campaigns, streamlining evaluation by applying standardized thresholds to ensure design viability and reduce failure risk.
Core Features & Use Cases
- Tiered filtering to prune designs by structural confidence, interface quality, and sequence liabilities.
- Composite ranking by combining multiple metrics (pLDDT, ipTM, PAE, SC, esm2_pll) into a single score.
- Risk assessment with severity scoring to identify actionable liabilities and guide redesign.
Quick Start
Upload your designs CSV and run the QC pipeline to filter by pLDDT > 0.85, ipTM > 0.50, scRMSD < 2.0, then compute the composite score and output top candidates for experimental testing.
Dependency Matrix
Required Modules
None requiredComponents
references
💻 Claude Code Installation
Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.
Please help me install this Skill: Name: protein-qc Download link: https://github.com/adaptyvbio/protein-design-skills/archive/main.zip#protein-qc Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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