pgdh-evaluate
CommunitySync and evaluate PGDH binder designs.
Authoralex-hh
Version1.0.0
Installs0
System Documentation
What problem does it solve?
This Skill streamlines the process of collecting, ranking, and evaluating protein binder designs for the 15-PGDH target, automating complex computational biology workflows.
Core Features & Use Cases
- Design Synchronization: Collects and standardizes design outputs from various tools into a central 'source of truth'.
- Automated Evaluation: Submits jobs for refolding, cross-validation, and scoring using computational resources.
- Ranking: Computes composite scores to rank designs based on multiple metrics.
- Use Case: After generating new protein binder designs, use this Skill to automatically sync them, assess their designability through refolding, validate their binding confidence with Boltz-2, and score their interaction strength with ipSAE, ultimately ranking them for further consideration.
Quick Start
Use the pgdh-evaluate skill to collect and rank designs from S3.
Dependency Matrix
Required Modules
None requiredComponents
scriptsreferences
💻 Claude Code Installation
Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.
Please help me install this Skill: Name: pgdh-evaluate Download link: https://github.com/alex-hh/in-silico-pgdh/archive/main.zip#pgdh-evaluate Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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