boltzgen-pgdh
CommunityDesign PGDH binders with BoltzGen.
Authoralex-hh
Version1.0.0
Installs0
System Documentation
What problem does it solve?
This Skill automates the design of protein binders targeting the 15-PGDH enzyme using the BoltzGen tool on the Lyceum platform, streamlining the drug discovery process.
Core Features & Use Cases
- Targeted Binder Design: Generates protein binders for specific strategies against 15-PGDH (active site, dimer interface, surface).
- Lyceum Integration: Orchestrates design jobs on the Lyceum GPU cluster.
- End-to-End Campaign Management: Supports the full lifecycle from design generation to result download.
- Use Case: Design novel protein binders that can block the active site of 15-PGDH for therapeutic intervention.
Quick Start
Run BoltzGen for the active site blocker strategy against 15-PGDH using the provided configuration.
Dependency Matrix
Required Modules
None requiredComponents
scriptsreferences
💻 Claude Code Installation
Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.
Please help me install this Skill: Name: boltzgen-pgdh Download link: https://github.com/alex-hh/in-silico-pgdh/archive/main.zip#boltzgen-pgdh Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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