dna-assembly

Community

Design DNA assembly primers with confidence.

AuthorZurybr
Version1.0.0
Installs0

System Documentation

What problem does it solve?

This Skill streamlines the complex process of designing primers for Golden Gate assembly and other multi-fragment DNA assembly workflows, reducing errors and increasing success rates.

Core Features & Use Cases

  • Primer Design Guidance: Provides step-by-step instructions for designing primers, including overhang selection and structure.
  • Assembly Simulation: Emphasizes the critical step of in-silico simulation to verify assembly outcomes before wet lab work.
  • Verification Checklist: Offers a comprehensive checklist to ensure all design parameters are met.
  • Use Case: A researcher needs to assemble five DNA fragments into a plasmid using Golden Gate cloning. This Skill guides them through designing the correct overhangs, checking for internal restriction sites, and simulating the final assembly to ensure the correct product is formed.

Quick Start

Use the dna-assembly skill to design primers for a 4-fragment linear Golden Gate assembly.

Dependency Matrix

Required Modules

None required

Components

references

💻 Claude Code Installation

Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.

Please help me install this Skill:
Name: dna-assembly
Download link: https://github.com/Zurybr/lefarma-skills/archive/main.zip#dna-assembly

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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