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correlation-methylation-epiFeatures

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Integrate methylation with chromatin signals.

Data & Analytics#integration#correlation#chromatin#methylation#epigenomics#atac-seq
AuthorBIsnake2001
Version1.0.0
Installs0

System Documentation

What problem does it solve?

This skill enables researchers to integrate CpG methylation data with chromatin features such as ATAC-seq signal, H3K27ac, H3K4me3, or other histone marks to explore regulatory relationships and epigenomic coordination.

Core Features & Use Cases

  • Integrated region-level table: Aligns methylation with chromatin signals to build a unified region table for downstream analysis.
  • Correlation analysis: Computes pairwise correlations between methylation and chromatin features across genomic regions.
  • Visualization: Generates heatmaps and scatter plots to visualize methylation–signal associations.
  • Use Case: Compare promoter and enhancer regions across conditions to identify coordinated epigenetic changes.

Quick Start

Provide CpG methylation BED and bigWig chromatin tracks for your regions and run the pipeline to generate a region_signal_table and correlations.

Dependency Matrix

Required Modules

None required

Components

Standard package

đź’» Claude Code Installation

Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.

Please help me install this Skill:
Name: correlation-methylation-epiFeatures
Download link: https://github.com/BIsnake2001/ChromSkills/archive/main.zip#correlation-methylation-epifeatures

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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