cellchat-cell-communication

Community

Map cell-cell communication networks.

Authorjaechang-hits
Version1.0.0
Installs0

System Documentation

What problem does it solve?

This Skill automates the inference, analysis, and visualization of intercellular communication networks from single-cell RNA-seq data, revealing how different cell types interact within a tissue or biological system.

Core Features & Use Cases

  • Infer Interactions: Identify ligand-receptor pairs mediating communication between cell groups.
  • Pathway Analysis: Aggregate interactions into signaling pathways (e.g., VEGF, MHC-II).
  • Network Visualization: Generate chord diagrams, heatmaps, and bubble plots to explore communication patterns.
  • Use Case: Understand how tumor cells communicate with immune cells in the tumor microenvironment to identify potential therapeutic targets.

Quick Start

Use the cellchat-cell-communication skill to infer and visualize cell-cell communication pathways from your Seurat object.

Dependency Matrix

Required Modules

CellChatSeuratNMFggplot2ggalluvialigraphdplyrpatchworkreticulatecirclizeRColorBrewer

Components

scriptsreferences

💻 Claude Code Installation

Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.

Please help me install this Skill:
Name: cellchat-cell-communication
Download link: https://github.com/jaechang-hits/SciAgent-Skills/archive/main.zip#cellchat-cell-communication

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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