bioinformatics-fundamentals

Community

Master core bioinformatics concepts for genomics.

AuthorDelphine-L
Version1.0.0
Installs0

System Documentation

What problem does it solve?

This Skill provides foundational knowledge of key bioinformatics concepts, enabling practitioners to understand file formats, sequencing data, and common data processing patterns, reducing debugging time.

Core Features & Use Cases

  • File Formats Overview: SAM/BAM, FASTQ/FASTA, BED, AGP, VCF, and their practical implications.
  • Sequencing Technologies: Illumina, PacBio HiFi, Hi-C basics and typical workflows.
  • Quality Metrics & Patterns: MAPQ, PHRED, N50, coverage, and common troubleshooting patterns.
  • Use Case: Debug alignment issues or validate AGP coordinates in a genome assembly.

Quick Start

Input a sample BAM and ask the skill to summarize common flags (0x1, 0x2, 0x4, etc.) and interpret MAPQ; or to generate a quick checklist for validating AGP coordinates.

Dependency Matrix

Required Modules

None required

Components

Standard package

💻 Claude Code Installation

Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.

Please help me install this Skill:
Name: bioinformatics-fundamentals
Download link: https://github.com/Delphine-L/claude_global/archive/main.zip#bioinformatics-fundamentals

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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