Hugh avatar

Hugh

Community

@hughyau

112Followers
|
26Public Repos
|
50Published Skills

One is All.

Skills Distribution
DomainAI Models & ...Structural Biology.. (35%)Single-Cell & Geno.. (20%)Scientific Visuali.. (15%)Remote Compute & M.. (15%)

Agent Skills by Hugh

Showing 50 vetted skills indexed across 4 GitHub repositories.

HughYauHughYau
59

fable4sci

Transforms scientific research questions into plain and image-rich fables preserving reasoning structure.

Community
Intermediate
HughYauHughYau
2.5k

scientific-visualization

Create publication-ready scientific figures with matplotlib, seaborn, and plotly.

Community
Advanced
HughYauHughYau
2.5k

figure-composer

Compose publication-grade multi-panel figures from a claim and data files.

Community
Advanced
HughYauHughYau
2.5k

learn

Guides learners through concepts using Socratic tutoring and scaffolded instruction.

Community
Intermediate
HughYauHughYau
2.5k

self-awareness

Query Claude Science session metadata, token usage, and execution history via SQLite.

Community
Advanced
HughYauHughYau
2.5k

using-model-endpoint

Call registered model endpoints over their native HTTP APIs from scoped inference kernels.

Community
Intermediate
HughYauHughYau
2.5k

alphafold2

Predicts protein monomer and multimer structures with AlphaFold2 via the ColabFold runner.

Community
Intermediate
HughYauHughYau
2.5k

solublempnn

Generates solubility-biased protein sequences from backbone structures using SolubleMPNN inverse folding.

Community
Intermediate
HughYauHughYau
2.5k

esmfold2

Predict protein, DNA, RNA, and ligand complex structures with ESMFold2 diffusion co-folding.

Community
Advanced
HughYauHughYau
2.5k

boltz

Predicts protein, nucleic-acid, and small-molecule complex structures with Boltz-2.

Community
Intermediate
HughYauHughYau
2.5k

remote-compute-ssh

Orchestrates job submission, monitoring, and result harvesting on SSH and SLURM compute hosts.

Community
Advanced
HughYauHughYau
2.5k

ligandmpnn

Design protein sequences around bound ligands, nucleic acids, and metals using LigandMPNN inverse folding.

Community
Intermediate
HughYauHughYau
2.5k

algorithmic-art

Creates generative art with p5.js using seeded randomness and interactive parameter controls.

Community
Intermediate
HughYauHughYau
2.5k

pdf-explore

Parses PDFs once into persistent text and images for targeted page navigation and extraction.

Community
Intermediate
HughYauHughYau
2.5k

scvi-tools

Trains scVI and scANVI models for batch-corrected single-cell RNA-seq embeddings and differential expression.

Community
Advanced
HughYauHughYau
2.5k

chai1

Predicts protein, nucleic-acid, and small-molecule complex structures with the Chai-1 diffusion model.

Community
Intermediate
HughYauHughYau
2.5k

scgpt

Embed and annotate single-cell expression data with the scGPT foundation model.

Community
Advanced
HughYauHughYau
2.5k

diffdock

Predict small-molecule binding poses against protein structures with DiffDock-L diffusion docking.

Community
Intermediate
HughYauHughYau
2.5k

remote-compute-modal

Runs GPU jobs on the user's own Modal account via sandboxed containers.

Community
Advanced
HughYauHughYau
2.5k

managed-model-endpoints

Registers local container or remote API model endpoints with a daemon for on-demand inference.

Community
Advanced
HughYauHughYau
2.5k

literature-review

Find, verify, and synthesize scientific literature using Crossref and OpenAlex APIs.

Community
Advanced
HughYauHughYau
2.5k

skill-creator

Create, evaluate, and iteratively improve AI agent skills with benchmarked testing.

Community
Advanced
HughYauHughYau
2.5k

indication-dossier

Generates a structured therapeutic indication dossier covering epidemiology, biology, standard of care, and clinical trials.

Community
Advanced
HughYauHughYau
2.5k

fair-esm2

Extract protein embeddings, mutation scores, and contact maps using Meta AI's ESM-2 models.

Community
Intermediate

Frequently Asked Questions About Hugh

FAQPage Schema
What tasks can I accomplish with HughYau's skill registry?▼

You can predict biomolecular structures with AlphaFold2, ESMFold2, Boltz-2, Chai-1, and OpenFold3; design protein sequences via ProteinMPNN and LigandMPNN; dock small molecules with DiffDock-L; analyze single-cell RNA-seq with scVI and scGPT; and produce publication-grade matplotlib figures and literature reviews.

Who is the target audience for these skills?▼

Computational biologists, structural biologists, protein engineers, and single-cell genomics researchers are the primary users. A secondary audience is software engineers who want disciplined practices like test-driven development, systematic debugging, Git worktrees, and subagent-driven code review.

How do the compute and model-serving skills work in practice?▼

The remote-compute-ssh skill orchestrates job submission and result harvesting on SSH and SLURM hosts, while remote-compute-modal runs GPU jobs in sandboxed Modal containers. The managed-model-endpoints skill registers local container or remote endpoints with a daemon for on-demand inference.

What prerequisites are needed to run the structural biology skills?▼

Structure prediction skills require access to GPU compute, either through SSH/SLURM clusters configured via compute-env-setup or a Modal account. Inputs are standard formats such as PDB backbone structures, DNA or protein sequences, and small-molecule definitions for docking and co-folding models.

Does the registry cover scientific communication and figure preparation?▼

Yes. The scientific-visualization, figure-composer, and figure-style skills produce publication-grade matplotlib, seaborn, and plotly figures, while literature-review synthesizes sources via Crossref and OpenAlex, and paper-narrative restructures manuscript story arcs from a handling editor's perspective.