TF-differential-binding
CommunityReveal TF binding changes across conditions.
AuthorBIsnake2001
Version1.0.0
Installs0
System Documentation
What problem does it solve?
DiffBind differential TF-binding analysis streamlines the identification of genomic regions with significantly different TF occupancy between conditions, enabling insights into regulatory changes.
Core Features & Use Cases
- Integrates read counting, normalization, and differential testing with DiffBind in R.
- Supports multi-condition comparisons (e.g., treatment vs control, wild-type vs mutant) and cross-cell-type analyses.
- Produces plots and summaries (PCA, heatmaps, volcano plots) and exports differential peak sets.
Quick Start
Provide a sample sheet with BAMs and peaks and run the DiffBind pipeline to obtain differential binding results.
Dependency Matrix
Required Modules
None requiredComponents
Standard package💻 Claude Code Installation
Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.
Please help me install this Skill: Name: TF-differential-binding Download link: https://github.com/BIsnake2001/ChromSkills/archive/main.zip#tf-differential-binding Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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