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structural-biology

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Validate structures and compare AlphaFold models.

Education & Research#validation#structure#confidence#alphafold#protein#discrepancies#rmsd
Authorjustaddcoffee
Version1.0.0
Installs0

System Documentation

What problem does it solve?

Structural-biology team members and AI-assisted workflows often struggle to reconcile experimental structures with AlphaFold predictions; this skill enables systematic comparison, validation, and interpretation of structural differences to guide experiments and modeling decisions.

Core Features & Use Cases

  • Per-residue deviation analysis between experimental and predicted structures.
  • AlphaFold confidence interpretation (pLDDT, PAE) integrated with structural comparisons.
  • Guided workflows for identifying conformational changes, domain orientations, and modeling limitations.

Quick Start

Ask it to compare your AlphaFold model against an experimental structure to identify confident regions and discordant areas.

Dependency Matrix

Required Modules

None required

Components

Standard package

💻 Claude Code Installation

Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.

Please help me install this Skill:
Name: structural-biology
Download link: https://github.com/justaddcoffee/open-science-skills/archive/main.zip#structural-biology

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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