seuratsubclustering

Community

Fine-grained re-clustering of cell subsets.

Authorpwwang
Version1.0.0
Installs0

System Documentation

What problem does it solve?

Performs fine-grained re-clustering on specific subsets of cells within a Seurat object to resolve heterogeneity and reveal hidden subpopulations.

Core Features & Use Cases

  • Complete clustering workflow on user-defined subsets, including PCA, UMAP, FindNeighbors, and FindClusters, to explore substructure within clusters or annotated cell types.
  • Supports metadata- or barcode-based subsetting, multiple resolutions, and case-based outputs to compare hierarchical clustering results.
  • Integrates with mutaters and subset expressions to tailor analyses for targeted biological questions, such as dissecting CD4 T cell or CD8 T cell heterogeneity.

Quick Start

Provide a Seurat object and a subset expression, and run the full re-clustering workflow on that subset.

Dependency Matrix

Required Modules

None required

Components

Standard package

💻 Claude Code Installation

Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.

Please help me install this Skill:
Name: seuratsubclustering
Download link: https://github.com/pwwang/immunopipe/archive/main.zip#seuratsubclustering

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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