scenic-gene-regulatory-network
CommunityInfer gene regulatory networks
Education & Research#gene regulatory network#grn#single-cell rna-seq#scenic#regulon#transcription factor#auc
AuthorStarlitnightly
Version1.0.0
Installs0
System Documentation
What problem does it solve?
This Skill automates the complex process of inferring gene regulatory networks (GRNs) from single-cell RNA sequencing data, identifying transcription factor activity and regulons.
Core Features & Use Cases
- GRN Inference: Predicts transcription factor to target gene links using advanced methods like RegDiffusion.
- Regulon Pruning & Scoring: Validates predicted links using cisTarget databases and quantifies regulon activity per cell (AUCell).
- Use Case: Analyze scRNA-seq data to discover master regulators controlling cell identity in a specific cell type, or to understand the transcriptional logic of cellular differentiation.
Quick Start
Run the SCENIC skill on your AnnData object to infer gene regulatory networks and score regulon activity.
Dependency Matrix
Required Modules
None requiredComponents
scriptsreferences
💻 Claude Code Installation
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Please help me install this Skill: Name: scenic-gene-regulatory-network Download link: https://github.com/Starlitnightly/omicclaw/archive/main.zip#scenic-gene-regulatory-network Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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