query-opentarget

What problem does it solve?

Researchers and clinicians need a fast, programmatic way to find and evaluate gene-disease associations, drug-target relationships, and supporting evidence across heterogeneous data sources; this Skill lets you retrieve and inspect those associations from the OpenTargets Platform to inform target selection and validation.

Core Features & Use Cases

• Search targets and diseases: look up genes by symbol or Ensembl ID and find associated diseases, or search diseases and return top associated targets.
• Evidence and drug annotations: retrieve evidence scores, datasource breakdowns, known drugs, mechanism of action, and clinical phase for target-drug links.
• Use Case: identify the top genetic targets for a disease of interest and list known drugs and supporting evidence to inform experimental prioritization.

Quick Start

Query OpenTargets for the top five targets associated with Alzheimer's disease and show their evidence scores and any known drugs.