What problem does it solve? Python developers face fragmented guidance across style, architecture, async patterns, packaging, and scientific computing, leading to inconsistent codebases and poor framework choices. This Skill consolidates decision frameworks and reference documentation so every Python task starts with the right architecture and toolchain. ## Core Features & Use Cases - Decision Frameworks: Choose between FastAPI vs Django, async vs sync, uv vs pixi, and project layouts based on project scale and workload type. - Production Patterns: Covers FastAPI dependency injection, SQLAlchemy 2.0 async, Pydantic validation, JWT auth, WebSockets, and structured error handling. - Toolchain & Packaging: Complete uv, pixi, ruff, mypy, and pytest workflows including lockfile strategy, Docker builds, and CI/CD pipelines. - Scientific & ML Stack: Reference guides for matplotlib visualization, PyTorch Geometric GNNs, and PathML computational pathology. - Use Case: When starting a new REST API with PostgreSQL, the Skill directs you to FastAPI with asyncpg, a layered src/ architecture, Pydantic schemas at boundaries, and a uv-based toolchain with pytest configuration. ## Quick Start Ask the assistant to help you design and scaffold a new Python project, such as a FastAPI service or data pipeline, and it will apply the appropriate architecture, style, and toolchain guidance.