pydeseq2

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Pythonic DESeq2 for differential expression analysis

Authorovachiever
Version1.0.0
Installs0

System Documentation

What problem does it solve?

PyDESeq2 provides a Python implementation of DESeq2 for differential expression analysis on bulk RNA-seq data, enabling Wald tests, multiple testing correction, and LFC shrinkage in Python.

Core Features & Use Cases

  • DESeq2-style normalization, dispersion estimation, and LFC fitting
  • Wald tests with BH FDR control
  • Optional apeGLM LFC shrinkage for visualization
  • Full workflow from counts + metadata to results

Quick Start

Load counts and metadata, run DESeq2 pipeline, and extract significant genes.

Dependency Matrix

Required Modules

pydeseq2pandasnumpyscipy

Components

scriptsreferences

💻 Claude Code Installation

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Name: pydeseq2
Download link: https://github.com/ovachiever/droid-tings/archive/main.zip#pydeseq2

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