pseudobulkdeg
CommunityRobust pseudo-bulk DEG analysis across samples.
Authorpwwang
Version1.0.0
Installs0
System Documentation
What problem does it solve?
Aggregates single-cell counts into sample-level pseudo-bulk data and identifies differentially expressed genes between conditions, accounting for biological replicates.
Core Features & Use Cases
- Supports complex experimental designs including batch effects, paired samples, and interactions.
- Enables DE analysis with DESeq2 or edgeR and automatically performs enrichment on significant markers.
- Applies per-cell-type analysis and produces publication-ready results across multiple conditions.
Quick Start
Provide a minimal configuration to compare two conditions after aggregating cells into pseudo-bulk samples.
Dependency Matrix
Required Modules
None requiredComponents
Standard package💻 Claude Code Installation
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Please help me install this Skill: Name: pseudobulkdeg Download link: https://github.com/pwwang/immunopipe/archive/main.zip#pseudobulkdeg Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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