proteomics-ptm
OfficialAnalyze post-translational modifications.
AuthorTianGzlab
Version1.0.0
Installs0
System Documentation
What problem does it solve?
This Skill automates the complex analysis of post-translational modifications (PTMs) in proteomics data, enabling researchers to understand protein regulation beyond simple abundance.
Core Features & Use Cases
- PTM Site Localization: Assess the confidence of PTM site identification using localization probability scores.
- PTM Type Analysis: Quantify and categorize different types of PTMs (e.g., phosphorylation, acetylation).
- Motif Analysis: Identify sequence motifs enriched around PTM sites to infer kinase specificity or functional context.
- Differential PTM Analysis: Quantify changes in PTM levels, accounting for protein abundance variations.
- Use Case: After a mass spectrometry experiment, use this Skill to identify all phosphorylated sites, determine their localization confidence, and find enriched motifs around these sites to hypothesize regulatory pathways.
Quick Start
Run proteomics-ptm analysis on the demo data.
Dependency Matrix
Required Modules
numpypandasscipy
Components
scriptsreferences
💻 Claude Code Installation
Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.
Please help me install this Skill: Name: proteomics-ptm Download link: https://github.com/TianGzlab/OmicsClaw/archive/main.zip#proteomics-ptm Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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