What problem does it solve? Preparing an R package for Bioconductor submission involves many evolving requirements: DESCRIPTION metadata, biocViews, NAMESPACE hygiene, executable vignettes, data provenance, size limits, and passing R CMD check plus BiocCheck in the current devel environment. This Skill provides a structured audit and maturation workflow so packages meet official Bioconductor expectations without one giant redesign PR. ## Core Features & Use Cases - Phased Readiness Audit: Walks through package identity, interoperability, DESCRIPTION, NAMESPACE, R code, documentation, vignettes, tests, data provenance, repository hygiene, and resource limits. - Ecosystem-First Philosophy: Enforces reuse of established Bioconductor classes (SummarizedExperiment, SingleCellExperiment, GRanges), generics, and public APIs instead of parallel package-specific machinery. - Semantic PR Decomposition: Classifies findings into submission blockers, correctness issues, documentation gaps, and optional improvements so readiness work ships as small reviewable changes. - Use Case: A maintainer with an existing R package using private dependency APIs and no vignette runs this audit to produce a submission readiness report, then fixes blockers in separate PRs before validating with R CMD build, R CMD check, and BiocCheck in the current devel environment. ## Quick Start Audit my R package for Bioconductor submission readiness and produce a report of blockers and recommended fixes.