phenotype-lab-spec

What problem does it solve?

This Skill enables researchers and clinicians to translate complex phenotype and laboratory value criteria into machine-executable definitions, ensuring reproducibility and scalable validation across large EHR datasets.

Core Features & Use Cases

• Computer-executable phenotype definitions: Create structured, reusable definitions for Population, Exposure, Outcome, and Covariates that can be run against EHR data.
• Lab value mapping and time-series handling: Define lab variable mappings, normal ranges, and longitudinal processing to support robust analyses.
• Validation planning and templates: Provide built-in validation templates (PPV targets, sensitivity targets) and evaluation plans to ensure clinical relevance.

Quick Start

Create a phenotype definition for an NDMM exposure to daratumumab using IMWG criteria, and generate an accompanying validation plan.