modulescorecalculator
CommunityConfigure module scores for single-cell analysis.
Authorpwwang
Version1.0.0
Installs0
System Documentation
What problem does it solve?
Enables per-cell module scoring in single-cell analyses by configuring and running Seurat's AddModuleScore and CellCycleScoring on a Seurat object to quantify pathway activity and functional states.
Core Features & Use Cases
- Supports per-cell scoring with user-defined gene sets (exhaustion, cytotoxicity, proliferation, cell cycle) and diffusion-map options.
- Integrates with Seurat-based workflows to generate S/G2M scores, ModuleScore columns, and post-processing metadata transformations.
- Useful for comparing functional states across clusters, trajectories, or after perturbations in scRNA-seq analyses.
Quick Start
Load a Seurat object and run ModuleScoreCalculator with your chosen gene sets to generate per-cell scores.
Dependency Matrix
Required Modules
None requiredComponents
Standard package💻 Claude Code Installation
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Please help me install this Skill: Name: modulescorecalculator Download link: https://github.com/pwwang/immunopipe/archive/main.zip#modulescorecalculator Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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