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local-methylation-profile

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Visualize local methylation around regions.

Data & Analytics#bioinformatics#visualization#genomics#profile#methylation#bed
AuthorBIsnake2001
Version1.0.0
Installs0

System Documentation

What problem does it solve?

Analyzes local DNA methylation profiles around user-provided genomic regions and visualizes the average methylation pattern around those regions (e.g. TSS, CTCF peaks).

Core Features & Use Cases

  • Always prompt user for which columns in the BED files are methylation fraction/percent. Never decide by yourself.
  • Generate profile: Bin methylation around regions (±flank, fixed bin size), aggregate mean±SE.
  • Visualize: Plot mean profile with ribbon and center line.

Quick Start

Provide methylation.bed and target_regions.bed along with the column indices for methylation fraction and coverage to generate the local methylation profile and its visualization.

Dependency Matrix

Required Modules

None required

Components

Standard package

💻 Claude Code Installation

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Please help me install this Skill:
Name: local-methylation-profile
Download link: https://github.com/BIsnake2001/ChromSkills/archive/main.zip#local-methylation-profile

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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