lib-pydeseq2

Official

Differential gene expression analysis

Authorbiomaps-infra
Version1.0.0
Installs0

System Documentation

What problem does it solve?

This Skill automates the complex process of identifying differentially expressed genes from bulk RNA-seq count data, enabling researchers to pinpoint genes that change significantly between experimental conditions.

Core Features & Use Cases

  • Differential Expression Analysis: Perform standard DESeq2 workflows for RNA-seq data.
  • Statistical Testing: Identify significant genes using Wald tests with FDR correction.
  • Visualization: Generate volcano and MA plots for interpreting results.
  • Use Case: Analyze RNA-seq data from a drug treatment experiment to find genes that are significantly upregulated or downregulated in the treated group compared to the control group.

Quick Start

Use the lib-pydeseq2 skill to analyze RNA-seq counts using a simple condition design and identify genes differentially expressed between treated and control samples.

Dependency Matrix

Required Modules

pydeseq2pandasnumpyscipyscikit-learnanndatamatplotlibseaborn

Components

scriptsreferences

💻 Claude Code Installation

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Please help me install this Skill:
Name: lib-pydeseq2
Download link: https://github.com/biomaps-infra/blender-opencode/archive/main.zip#lib-pydeseq2

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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