lib-esm

What problem does it solve?

This Skill provides a comprehensive toolkit for advanced protein design, generation, and analysis using state-of-the-art AI models like ESM3 and ESM C.

Core Features & Use Cases

• Protein Sequence Generation: Design novel protein sequences with desired properties using ESM3's generative capabilities.
• Structure Prediction & Inverse Folding: Predict 3D protein structures from sequences or design sequences that fold into a target structure.
• Protein Embeddings: Generate high-quality embeddings for downstream tasks like classification, similarity analysis, and clustering using ESM C.
• Function Conditioning: Generate proteins with specific functional annotations or predict function from sequence.
• Use Case: A researcher needs to design a new enzyme with enhanced catalytic activity. They can use this Skill to generate candidate sequences, predict their structures, and analyze their functional potential.

Quick Start

Use the lib-esm skill to generate a novel protein sequence of 100 residues with moderate diversity.