known-motif-enrichment

Community

Identify known motif enrichment in peaks using HOMER.

AuthorBIsnake2001
Version1.0.0
Installs0

System Documentation

What problem does it solve?

Performs known motif enrichment analysis on genomic peaks or promoter regions using HOMER, identifying enrichment of known transcription factor motifs from established databases.

Core Features & Use Cases

  • HOMER-based motif enrichment: detects enrichment of known TF motifs in peak sets or promoter regions.
  • Flexible inputs: accepts BED, narrowPeak, broadPeak, or gene lists for promoter-focused analysis.
  • Comprehensive outputs: produces results directories with motif tables, logos, and detailed logs for reproducibility.
  • Typical use case: discover TFs likely driving regulation in ChIP-seq or ATAC-seq peak data.

Quick Start

Provide your input peak file (BED, narrowPeak, or broadPeak) or a gene list and run the HOMER-based known motif enrichment workflow to generate results.

Dependency Matrix

Required Modules

None required

Components

Standard package

💻 Claude Code Installation

Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.

Please help me install this Skill:
Name: known-motif-enrichment
Download link: https://github.com/BIsnake2001/ChromSkills/archive/main.zip#known-motif-enrichment

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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