hypogenic

Generate and test hypotheses from datasets using large language models.

1|Updated Mar 19, 2026
One-click install
npx skills add https://github.com/JosephWoodall/noosphere --skill hypogenic-josephwoodall
Or copy as Structured Prompt for Agent▼
Please help me install this Agent Skill.
Skill: hypogenic
Source: https://github.com/JosephWoodall/noosphere/tree/main/.agent/skills/hypogenic
Command: npx skills add https://github.com/JosephWoodall/noosphere --skill hypogenic-josephwoodall

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill includes references (resource) components.

What problem does it solve?

Hypogenic automates hypothesis generation and testing using large language models to accelerate scientific discovery, reducing manual, error-prone ideation and interpretation cycles.

Core Features & Use Cases

  • Automated Hypothesis Generation: generate hypotheses from data and literature using hypoGeniC, HypoRefine, and Union methods.
  • Literature Integration & Evaluation: combine literature-derived and data-driven hypotheses with iterative refinement.
  • Flexible Workflow: CLI and Python API support, config-driven prompts, and optional literature-processing steps.

Quick Start

Run hypogenic_generation with your task config to generate hypotheses, then use hypogenic_inference to evaluate them.

Frequently Asked Questions about hypogenic

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I automate hypothesis generation from my research datasets?▼

Hypothesis generation uses LLMs to evaluate data-driven propositions against your datasets. It supports data-driven methods and literature-informed refinement to accelerate scientific discovery across domains like deception detection and mental health indicators.

Can I integrate literature processing into my hypothesis testing workflow?▼

Yes, literature integration combines literature-derived and data-driven hypotheses with iterative refinement. Optional reference processing components allow you to incorporate existing research directly into your hypothesis generation and evaluation pipeline.

Do I need a specific Python environment to use LLMs for hypothesis generation?▼

You need a Python environment that supports CLI and API access for LLM interaction. The workflow relies on YAML-configurable task structures and prompt templates for observations, generation, inference, and relevance checking without external dependencies.

What is the best way to refine hypotheses generated from large language models?▼

The best approach uses iterative refinement methods like HypoRefine to combine literature-derived and data-driven hypotheses. Adaptive prompt templates perform relevance checking to improve hypothesis accuracy across research domains.

What domains are supported by automated hypothesis generation tools?▼

Automated hypothesis generation supports domains such as deception detection, AI-generated content identification, and mental health indicators. The config-driven prompts and data pipelines allow application across diverse scientific research fields.