harmony-batch-correction

What problem does it solve?

This Skill addresses the challenge of removing technical batch effects from single-cell omics data, ensuring that biological variation is preserved while integrating datasets from different sources.

Core Features & Use Cases

• Batch Effect Removal: Integrates datasets by regressing out technical variations from PCA embeddings.
• Scalability: Efficiently handles datasets with millions of cells.
• Use Case: Combine scRNA-seq data from multiple experiments or labs to identify cell types consistently across all batches.

Quick Start

Use the harmony-batch-correction skill to integrate the provided AnnData object using the 'batch' column.