genomics-vcf-operations
OfficialVCF analysis and filtering
AuthorTianGzlab
Version1.0.0
Installs0
System Documentation
What problem does it solve?
This Skill automates complex VCF file manipulations and statistical analyses, which are typically time-consuming and error-prone when done manually or with intricate command-line tools.
Core Features & Use Cases
- Variant Statistics: Mirrors
bcftools statsfor Ti/Tv ratio, variant type counts (SNP, INDEL, MNP, COMPLEX), and quality metrics. - Filtering: Apply filters based on QUAL score, Depth (DP), and other INFO fields.
- VCF Merging: Combines multiple VCF files into a single, coherent file.
- Use Case: Quickly filter a large VCF file to keep only high-quality PASS variants with a minimum depth of 10x, and then generate a summary report of the variants.
Quick Start
Run the genomics-vcf-operations skill to filter the input VCF file 'variants.vcf' keeping only variants with a minimum quality of 30.
Dependency Matrix
Required Modules
None requiredComponents
scripts
💻 Claude Code Installation
Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.
Please help me install this Skill: Name: genomics-vcf-operations Download link: https://github.com/TianGzlab/OmicsClaw/archive/main.zip#genomics-vcf-operations Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
Agent Skills Search Helper
Install a tiny helper to your Agent, search and equip skill from 223,000+ vetted skills library on demand.