genomics-epigenomics

What problem does it solve?

This Skill automates the complex process of analyzing epigenomic data, such as ATAC-seq and ChIP-seq, making it easier to identify key regulatory regions and understand gene accessibility.

Core Features & Use Cases

• Peak Calling: Identifies regions of open chromatin or protein binding using MACS3.
• Motif Enrichment: Discovers transcription factor binding motifs within identified peaks.
• Quality Control: Assesses the quality of sequencing data and peak calls.
• Use Case: A researcher has ATAC-seq data and wants to find all accessible genomic regions and identify which transcription factors are likely binding to them.

Quick Start

Run ATAC peak calling with MACS3 on this bam file.