genetics-selfdecode-lookup

What problem does it solve?

This Skill enables researchers and enthusiasts to access imputed SNP genotypes from SelfDecode, expanding genetic coverage beyond raw 23andMe data and facilitating deeper genotype-phenotype exploration.

Core Features & Use Cases

• Imputed SNP lookup: Retrieve genotypes for SNPs not present in raw data using SelfDecode's imputed dataset.
• Per-SNP and batch queries: Efficiently fetch single SNP results or multiple SNPs in a single request.
• Secure authentication & caching: Manage JWT tokens via profile config, cache results locally with a TTL, and prompt token refresh when needed.
• Use Case: A researcher wants to verify the APOE variant across imputed data to assess risk in a larger SNP set.

Quick Start

• Ensure SelfDecode credentials are configured in your profile YAML under data_sources.selfdecode.
• Start Claude Code in the skill directory and request a lookup, for example: "Check genotype for rs429358 using SelfDecode."
• If authentication fails, follow the prompt to refresh the JWT token and retry.