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functional-enrichment

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GO/KEGG enrichment from regions or genes with HOMER.

Education & Research#go#ggplot2#functional-enrichment#kegg#homer#genomic-regions#gene-lists
AuthorBIsnake2001
Version1.0.0
Installs0

System Documentation

What problem does it solve?

Perform GO and KEGG functional enrichment using HOMER from genomic regions (BED/narrowPeak/broadPeak) or gene lists, and produce R-based visualizations to aid interpretation.

Core Features & Use Cases

  • Map regions to genes using HOMER annotatePeaks.pl
  • Run GO enrichment with findGO.pl and -go options
  • Run KEGG enrichment with -kegg and related options
  • Generate tidy result tables and R plots (barplot/dotplot) for quick visualization
  • Provide QC checks for genome version, chromosome naming, and input formats
  • Support gene-list workflows and direct-from-BED enrichment for streamlined analyses

Quick Start

Provide your region or gene list inputs and run the enrichment workflow to generate GO/KEGG results and accompanying plots.

Dependency Matrix

Required Modules

None required

Components

Standard package

💻 Claude Code Installation

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Please help me install this Skill:
Name: functional-enrichment
Download link: https://github.com/BIsnake2001/ChromSkills/archive/main.zip#functional-enrichment

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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