foldseek

Official

Find structural similarities quickly with Foldseek.

Authoradaptyvbio
Version1.0.0
Installs0

System Documentation

What problem does it solve?

This skill automates structure similarity search for proteins using Foldseek.

Core Features & Use Cases

It supports locating homologous structures, remote homologs, and clustering across large structure databases such as PDB and AlphaFold DB, enabling rapid assessment of design plausibility.

  • Structural homology search
  • Remote homolog detection
  • Clustering and similarity ranking
  • Use Case: identify designs with desired fold similarity to known structures

Quick Start

Use Foldseek to search a query structure against a database: foldseek easy-search query.pdb pdb100 results.m8 tmp/ --format-output query,target,pident,alnlen,evalue,bits

Dependency Matrix

Required Modules

None required

Components

Standard package

💻 Claude Code Installation

Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.

Please help me install this Skill:
Name: foldseek
Download link: https://github.com/adaptyvbio/protein-design-skills/archive/main.zip#foldseek

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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