esm

What problem does it solve?

This Skill provides a comprehensive toolkit for working with advanced protein language models, enabling complex protein design, sequence generation, structure prediction, and function analysis without requiring deep ML expertise.

Core Features & Use Cases

• Protein Sequence Generation: Design novel protein sequences with specific properties using ESM3.
• Structure Prediction & Inverse Folding: Predict 3D protein structures from sequences or design sequences from target structures.
• Protein Embeddings: Generate high-quality embeddings for downstream tasks like classification and similarity analysis using ESM C.
• Use Case: A researcher needs to design a new enzyme with enhanced stability. They can use ESM3 to generate sequences predicted to fold correctly and exhibit desired functional annotations, then use ESM C embeddings to analyze the diversity of generated variants.

Quick Start

Use the esm skill to generate a novel protein sequence based on a partial prompt.