depmap
CommunityUncover cancer gene dependencies.
Education & Research#bioinformatics#cancer genomics#drug targets#depmap#gene dependency#crispr screens
AuthorYezez9
Version1.0.0
Installs0
System Documentation
What problem does it solve?
This Skill provides access to the Cancer Dependency Map (DepMap) data, enabling researchers to identify genes essential for cancer cell survival and pinpoint potential therapeutic targets.
Core Features & Use Cases
- Query Gene Dependencies: Retrieve CRISPR knockout scores for specific genes across hundreds of cancer cell lines.
- Identify Selective Vulnerabilities: Find genes that are essential only in certain cancer types or subtypes.
- Biomarker Discovery: Correlate gene essentiality with mutations, expression, or copy number alterations.
- Use Case: Investigate if the gene 'KRAS' is selectively essential in lung cancer cell lines compared to other cancer types.
Quick Start
Use the depmap skill to find cell lines selectively dependent on the gene 'KRAS' within the 'Lung' cancer type.
Dependency Matrix
Required Modules
None requiredComponents
scriptsreferences
💻 Claude Code Installation
Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.
Please help me install this Skill: Name: depmap Download link: https://github.com/Yezez9/Research-Agent/archive/main.zip#depmap Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
Agent Skills Search Helper
Install a tiny helper to your Agent, search and equip skill from 223,000+ vetted skills library on demand.