db-gtex

Official

Explore tissue-specific gene expression.

Authorbiomaps-infra
Version1.0.0
Installs0

System Documentation

What problem does it solve?

This Skill helps researchers interpret genetic variants by querying the Genotype-Tissue Expression (GTEx) database to understand gene expression patterns and regulatory effects across different human tissues.

Core Features & Use Cases

  • Gene Expression Analysis: Retrieve median gene expression levels (TPM) across 54 human tissues.
  • eQTL and sQTL Lookup: Identify genetic variants associated with gene expression (eQTLs) or splicing (sQTLs) in specific tissues.
  • GWAS Variant Interpretation: Link non-coding GWAS variants to potential target genes by finding eQTLs in relevant tissues.
  • Use Case: Investigate how a specific genetic variant might affect the expression of a gene in the brain versus the liver.

Quick Start

Query GTEx for the median expression of the gene APOE across all tissues.

Dependency Matrix

Required Modules

requestspandas

Components

references

💻 Claude Code Installation

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Please help me install this Skill:
Name: db-gtex
Download link: https://github.com/biomaps-infra/blender-opencode/archive/main.zip#db-gtex

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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