db-clinvar

Official

Query ClinVar for variant significance.

Authorbiomaps-infra
Version1.0.0
Installs0

System Documentation

What problem does it solve?

This Skill helps researchers and clinicians quickly access and interpret clinical significance data for genetic variants from the NCBI ClinVar database, streamlining genomic data analysis and interpretation.

Core Features & Use Cases

  • Variant Search: Find variants by gene, position, or clinical significance.
  • Interpretation: Understand pathogenicity classifications and review status.
  • Data Access: Utilize E-utilities API or download bulk data via FTP.
  • Use Case: A geneticist needs to determine if a specific variant in the BRCA1 gene is pathogenic for a patient. They use this Skill to query ClinVar, retrieve the variant's classification, and review the supporting evidence.

Quick Start

Use the db-clinvar skill to search for pathogenic variants in the BRCA1 gene.

Dependency Matrix

Required Modules

None required

Components

references

💻 Claude Code Installation

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Please help me install this Skill:
Name: db-clinvar
Download link: https://github.com/biomaps-infra/blender-opencode/archive/main.zip#db-clinvar

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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