db-cbioportal

What problem does it solve?

This Skill provides programmatic access to vast cancer genomics datasets, enabling researchers to query mutations, copy number alterations, and clinical data across numerous cancer studies.

Core Features & Use Cases

• Data Exploration: Investigate mutation frequencies, co-occurrence patterns, and alteration profiles for specific genes.
• Survival Analysis: Correlate genomic alterations with patient survival outcomes.
• Pan-Cancer Analysis: Compare genomic landscapes across different cancer types.
• Use Case: Determine the mutation frequency of the TP53 gene in breast cancer (BRCA_TCGA) and compare it to its frequency in lung adenocarcinoma (LUAD_TCGA).

Quick Start

Use the db-cbioportal skill to get the mutation frequency of TP53 in the BRCA_TCGA study.