coot-NCS-reference-guidance

Community

NCS reference guidance for consistent builds.

Authorpemsley
Version1.0.0
Installs0

System Documentation

What problem does it solve?

This Skill helps structure scientists ensure consistent sequences and coordinates across multiple NCS-related copies in COOT. It guides users to reference symmetry-related molecules to align sequences and references, reducing build errors and improving model accuracy.

Core Features & Use Cases

  • Compare sequences between related chains to identify discrepancies and ensure consistency across NCS copies.
  • Use the better-built chain as a template to guide rebuilding of other chains, reducing manual trial-and-error.
  • Copy and apply NCS-based fragments across chains, followed by targeted refinements and validation to improve model quality.

Quick Start

Load your molecule in COOT, enable NCS ghosts, and run the example workflow to compare A and B chains, build missing residues from the better copy, and refine with flanking residues.

Dependency Matrix

Required Modules

None required

Components

Standard package

💻 Claude Code Installation

Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.

Please help me install this Skill:
Name: coot-NCS-reference-guidance
Download link: https://github.com/pemsley/coot/archive/main.zip#coot-ncs-reference-guidance

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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