clinpgx

What problem does it solve?

ClinPGx simplifies retrieving authoritative pharmacogenomic gene-drug information by querying the ClinPGx REST API and aggregating clinical annotations, guideline recommendations, and regulatory drug label statements so researchers and clinicians can quickly find evidence for gene-drug interactions.

Core Features & Use Cases

• Gene lookup: Retrieve gene metadata, allele types, and CPIC gene flags for pharmacogenes such as CYP2D6 or CYP2C19.
• Drug lookup: Search drugs by name and collect linked clinical annotations and FDA/EMA label statements.
• Gene-drug pair analysis: Aggregate clinical annotations, CPIC/DPWG guidelines, and drug labels for specific gene-drug pairs and produce reproducible reports and CSV tables.
• Operational features: Built-in rate limiting (2 req/sec), local 24-hour caching, CLI and programmatic API integration, and standardized JSON result export for reproducibility.
• Use case: Query a list of pharmacogenes to generate a markdown report and CSV tables summarizing clinical evidence and dosing guidance for flagged gene-drug pairs.

Quick Start

Look up CYP2D6 and warfarin on ClinPGx and generate a markdown report with CSV tables of clinical annotations, guidelines, and drug labels.