ChIPseq-QC

Community

ChIP-seq QC: NSC/RSC and FRiP metrics

AuthorBIsnake2001
Version1.0.0
Installs0

System Documentation

What problem does it solve?

This skill provides QC metrics for ChIP-seq data by computing cross-correlation (NSC/RSC) and FRiP from aligned BAMs and called peaks, enabling assessment of ChIP data quality before downstream analysis.

Core Features & Use Cases

  • Cross-correlation analysis: calculates NSC and RSC to evaluate signal enrichment and data quality.
  • FRiP computation: estimates the fraction of reads within peak regions to gauge enrichment.
  • Output & workflow integration: organizes results under an all_chip_qc directory and supports integration with downstream QC reporting.

Quick Start

Run this skill after peak calling to produce QC metrics for your ChIP-seq BAM and peak files.

Dependency Matrix

Required Modules

None required

Components

Standard package

💻 Claude Code Installation

Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.

Please help me install this Skill:
Name: ChIPseq-QC
Download link: https://github.com/BIsnake2001/ChromSkills/archive/main.zip#chipseq-qc

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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