celltypeannotation

Annotate scRNA-seq clustering results with cell type labels using multiple tools.

22|4|Updated May 18, 2021
One-click install
npx skills add https://github.com/pwwang/immunopipe --skill celltypeannotation
Or copy as Structured Prompt for Agent▼
Please help me install this Agent Skill.
Skill: celltypeannotation
Source: https://github.com/pwwang/immunopipe/tree/main/skills/celltypeannotation
Command: npx skills add https://github.com/pwwang/immunopipe --skill celltypeannotation

SYSTEM DOCUMENTATION & REQUIREMENTS

What problem does it solve?

Annotates clustering results with biological cell type labels to give meaningful identities to clusters, enabling downstream interpretation and comparison across samples.

Core Features & Use Cases

  • Direct assignment
  • ScType
  • scCATCH
  • hitype
  • CellTypist
  • Seamless integration with Seurat objects and h5ad inputs for PBMC and multi-sample datasets

Quick Start

Supply your Seurat clustering results and run this workflow to obtain labeled cell types for each cluster.

Frequently Asked Questions about celltypeannotation

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I annotate scRNA-seq clustering results with biological cell types?▼

Cell-type annotation for scRNA-seq data is performed by applying automated tools like ScType, scCATCH, hitype, or CellTypist to assign biological labels to clusters for downstream interpretation.

Can I use CellTypist or scCATCH to label immune cell clusters in a Seurat object?▼

Yes, you can use CellTypist and scCATCH for immune cell datasets. The workflow seamlessly integrates with Seurat objects to deliver labeled cell types for each cluster.

Does this cell-type annotation workflow support h5ad files and multi-sample studies?▼

Yes, the workflow supports h5ad inputs and applies to post-clustering analyses across multi-sample datasets, enabling configurable input formats and output columns for reproducible annotation.

What is the best way to compare direct assignment vs automated annotation tools for scRNA-seq data?▼

You can compare direct assignment against automated tools like ScType, scCATCH, hitype, or CellTypist by configuring tool choices and tissue specifications within the same reproducible annotation workflow.

How do I configure tissue specifications and database paths for scCATCH or ScType?▼

You can configure tissue specifications, database paths, tool choices, and output columns within the workflow to ensure annotation tools correctly match your specific scRNA-seq dataset context.