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cellcellcommunication

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Infer cell-cell signaling from single-cell data.

Data & Analytics#bioinformatics#ligand-receptor#scRNA-seq#network-inference#cell-cell#liana+
Authorpwwang
Version1.0.0
Installs0

System Documentation

What problem does it solve?

Infer ligand-receptor interactions and cell-cell communication networks from single-cell RNA-seq data using the LIANA+ framework. It identifies signaling events between cell types based on gene expression patterns and curated ligand-receptor interaction databases.

Core Features & Use Cases

  • Inference using LIANA+ with multiple methods to assess signaling between cell types and compare patterns across conditions or tissues.
  • Guidance on resource selection, parameter tuning (species, groupby, expr_prop, min_cells), and downstream visualization.
  • Use Case: Compare communication patterns between healthy and diseased tissues to identify key mediators of cellular crosstalk.

Quick Start

Provide a Seurat or AnnData object and run the LIANA+ workflow to infer ligand-receptor interactions and output network results.

Dependency Matrix

Required Modules

None required

Components

Standard package

💻 Claude Code Installation

Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.

Please help me install this Skill:
Name: cellcellcommunication
Download link: https://github.com/pwwang/immunopipe/archive/main.zip#cellcellcommunication

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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