cdr3clustering
CommunityCluster TCR/BCR clones by CDR3 with Faiss.
Authorpwwang
Version1.0.0
Installs0
System Documentation
What problem does it solve?
Clustering of TCR/BCR clones by CDR3 sequences to reveal related clonotypes and public motifs, enabling downstream clonotype analysis.
Core Features & Use Cases
- Clusters by CDR3 sequences using GIANA or ClusTCR (Faiss-based) and annotates with a CDR3_Cluster column.
- Flexible method and chain selection to suit dataset size and analysis goals.
- Use Case: Investigate convergent recombination and cross-sample public clonotypes for downstream analyses.
Quick Start
Run the CDR3Clustering process on your TCR/BCR data to generate the CDR3_Cluster metadata.
Dependency Matrix
Required Modules
None requiredComponents
Standard package💻 Claude Code Installation
Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.
Please help me install this Skill: Name: cdr3clustering Download link: https://github.com/pwwang/immunopipe/archive/main.zip#cdr3clustering Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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