bio-binning-qc

Community

End-to-end MAG binning, refinement, and QC

Authorfmschulz
Version1.0.0
Installs0

System Documentation

What problem does it solve?

Bins derived from metagenomic data often require manual curation and multi-tool QC to meet publication-ready quality. This Skill coordinates automated binning, refinement, and risk-based QC gating to produce high-quality MAGs with transparent criteria.

Core Features & Use Cases

  • Multi-binner coordination: run and optionally refine bins with tools like MetaBAT2, SemiBin2, and QuickBin to maximize recovery and purity.
  • Domain-aware QC: apply CheckM2 for bacteria/archaea, EukCC for eukaryotes, and GUNC for chimerism to filter high-quality bins.
  • Reproducible workflows: orchestrate inputs, binning steps, QC checks, and outputs for consistent MAG pipelines suitable for downstream analyses or publication.
  • Use Case: in large-scale gut microbiome projects, quickly obtain a set of high-quality MAGs with documentation-ready QC metrics.

Quick Start

Run the workflow on your contig assemblies to generate MAG bins and pass QC gates before downstream analyses.

Dependency Matrix

Required Modules

None required

Components

Standard package

💻 Claude Code Installation

Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.

Please help me install this Skill:
Name: bio-binning-qc
Download link: https://github.com/fmschulz/omics-skills/archive/main.zip#bio-binning-qc

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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