antibody-structure-prediction-tfold

Predict antibody and nanobody structures from sequences using tfold-based models.

1.1k|132|Updated Apr 13, 2023
One-click install
npx skills add https://github.com/PharMolix/OpenBioMed --skill antibody-structure-prediction-tfold
Or copy as Structured Prompt for Agent▼
Please help me install this Agent Skill.
Skill: antibody-structure-prediction-tfold
Source: https://github.com/PharMolix/OpenBioMed/tree/main/skills/antibody-structure-prediction-tfold
Command: npx skills add https://github.com/PharMolix/OpenBioMed --skill antibody-structure-prediction-tfold

SYSTEM DOCUMENTATION & REQUIREMENTS

What problem does it solve?

Predict antibody and nanobody structures from sequence data.

Core Features & Use Cases

  • Antibody and nanobody structure prediction from heavy/light chain sequences.
  • Antigen-antibody complex structure prediction from paired sequences.

Quick Start

Provide heavy and light chain sequences to generate the predicted antibody structure.

Frequently Asked Questions about antibody-structure-prediction-tfold

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I predict an antibody structure from sequence data?▼

To predict an antibody structure from sequence data, you provide the heavy and light chain sequences as input to generate the predicted 3D structure using the tfold-based local prediction model.

Can I predict nanobody structures using this tool?▼

Yes, you can predict nanobody structures by providing the specific sequence data to the local tfold-based prediction environment, which supports both standard antibodies and nanobodies.

How do I predict an antigen-antibody complex structure?▼

You can predict an antigen-antibody complex structure by providing paired sequences of the antibody and antigen to the local tfold model, which will generate the predicted complex structure.

Do I need a local GPU to run antibody structure prediction with tfold?▼

Yes, you need a local GPU because the antibody structure prediction process runs in a local environment and requires local GPU hardware along with the necessary dependencies and models.

What is the best way to model an antigen-antibody complex locally?▼

The best way to model an antigen-antibody complex locally is to use a tfold-based model with paired sequences, which runs directly on your local GPU to generate the complex structure.