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adaptyv

Submits protein sequences to the Adaptyv Bio Foundry API for experimental binding and thermostability assays.

46.6k|4.2k|Updated Oct 19, 2025
Search Tags:#cloud lab#adaptyv#protein engineering#bli#thermostability#binding assay#foundry api
One-click install
npx skills add https://github.com/K-Dense-AI/claude-scientific-skills --skill adaptyv-k-dense-ai
Or copy as Structured Prompt for Agent▼
Please help me install this Agent Skill.
Skill: adaptyv
Source: https://github.com/K-Dense-AI/claude-scientific-skills/tree/main/skills/adaptyv
Command: npx skills add https://github.com/K-Dense-AI/claude-scientific-skills --skill adaptyv-k-dense-ai

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires adaptyv-sdk, and includes references (resource) components.

What problem does it solve? Designing and running wet-lab protein experiments requires coordinating with a cloud lab, tracking experiment status, and retrieving assay results, which is error-prone when done manually through a web UI. ## Core Features & Use Cases - Experiment Design & Submission: Create affinity, screening, thermostability, expression, and fluorescence experiments via the Foundry REST API or the adaptyv-sdk Python client, with cost estimation before committing. - Lifecycle & Results Tracking: Follow experiments from Draft through Done, use webhooks for status transitions, and retrieve KD/kon/koff kinetics or Tm values when results are ready. - Use Case: A protein engineer has 50 candidate binder sequences for EGFR. Use this Skill to look up the EGFR target, estimate screening cost, submit the batch via BLI, and poll for binding results. ## Quick Start Use the adaptyv skill to submit my protein sequences for a BLI binding screen against EGFR and estimate the cost first.

Frequently Asked Questions about adaptyv

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I submit protein sequences to Adaptyv Foundry?▼

Create an experiment with the FoundryClient by providing an experiment_spec containing the experiment_type, method, target_id, and a map of amino acid sequences, then call experiments.submit. Sequences can only be added while the experiment is in Draft status.

How to install the adaptyv-sdk Python package?▼

The adaptyv-sdk 0.1.0 beta is not on PyPI, so install it from GitHub with uv pip install "git+https://github.com/adaptyvbio/adaptyv-sdk.git". Set ADAPTYV_API_KEY and ADAPTYV_API_URL as environment variables before use.

What experiment types does the Adaptyv Foundry API support?▼

The API supports affinity and screening experiments using BLI or SPR methods, plus thermostability, expression, and fluorescence assays. Binding experiments require a target_id from the target catalog; the other types do not.

Does the Adaptyv API support webhooks for experiment status?▼

Yes, pass a webhook_url when creating an experiment and Adaptyv POSTs to that URL on every status transition with the experiment ID, previous status, and new status. Alternatively, poll the experiment or updates endpoints.

Why can't I add sequences to my Adaptyv experiment?▼

Sequences can only be appended to experiments in Draft status; the API returns a 409 error otherwise. Once an experiment is submitted and moves to WaitingForConfirmation, its sequence set is locked.

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